Vascular Disease Management

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CLINICAL EXPERIENCE WITH A NEW HYBRID CORONARY WIRE
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Target Audience: Physicians, nurses, and technologists.
This activity is supported by an educational grant from Terumo Medical Corporation.

Clinical Review

Bare-Metal Versus Drug-Coated Intracoronary Stents in Clinical Practice: Are There Guidelines?




VOLUME: 6 PUBLICATION DATE: Sep 01 2009
Issue Number: 
Volume 6 , Issue 5 (Sept/Oct 2009)
Srihari S. Naidu, MD

Introduction

The development of bare-metal stents (BMS) and optimal post-procedure antiplatelet therapy in the mid 1990s resulted in marked reductions in acute and subacute stent thrombosis, bleeding complications, negative remodeling, and acute vessel recoil, and a consequent dramatic rise in procedural success. Yet, intermediate-term outcomes remained hampered by restenosis from aggressive neointimal hyperplasia. The advent of drug-coated stents, which impede the growth of neointima while maintaining the strengths of BMS, heralded their widespread utilization to approximately 90% o



Does Microparticle Size Affect Bland Embolization Outcomes of Local Treatment for Liver Malignancies?




VOLUME: 6 PUBLICATION DATE: Sep 01 2009
Issue Number: 
Volume 6 , Issue 5 (Sept/Oct 2009)
Guido Bonomo, MD, Lorenzo Monfardini, MD, Paolo Della Vigna, MD, Gianluigi Orgera, MD, Vittorio Pedicini, MD, Franco Orsi, MD

Introduction

Treatment options for primary liver tumors (i.e., hepatocellular carcinoma or HCC) and metastatic liver neoplasms have increased in the past decade in response to the incidence of these tumors; HCC is the most common primary liver cancer, while liver tumors are the sixth most common cancer and the third most common cause of cancer-related death globally.1,2 The incidence of liver cancer in the United States and Western Europe is increasing.3,4 Liver metastases from colorectal cancer (CRC) develop in 50% of patients.5

While liver resection remains the gold standard in



Gene Therapy in Critical Limb Ischemia




VOLUME: 6 PUBLICATION DATE: Aug 01 2009
Issue Number: 
Volume 6, Issue 4 (July/August 2009)


authors:
1Hong H. Keo, MD, 2Alan T. Hirsch, MD, 1Iris Baumgartner, MD, 3Sigrid Nikol, MD,
2Timothy D. Henry, MD

________________________________

Abstract

Critical limb ischemia (CLI) represents the most severe stage of atherosclerotic lower extremity peripheral artery disease (PAD), and CLI prevalence is expected to increase as the population ages. The current standard of care for CLI relies on direct revascularization, either by endovascular techniques or open surgical approaches, as there are few effective medical treatments for this condition. Therapeutic angi



Interventional Treatment Options for Small Saphenous Varicose Veins




VOLUME: 6 PUBLICATION DATE: Aug 01 2009
Issue Number: 
Volume 6, Issue 4 (July/August 2009)


authors:
Caroline D. Rodd, MD, FRCS, Alison M. Young, MBBS, Jonothan J. Earnshaw, DM, FRCS

___________________________

Introduction

Varicose veins are common, and affect nearly a third of adults in Western societies. Although women present more frequently for treatment, Lee et al observed a significantly higher age-adjusted prevalence of varicose veins in men (40% vs. 32% in women).1 Patients present with a variety of symptoms that they attribute to their varicose veins, including pain, heaviness, burning, itching, superficial thrombophlebitis, skin changes, and



The Rationale for PFO Closure: A Series of Arguments For or Against




VOLUME: 6 PUBLICATION DATE: Jun 01 2009
Issue Number: 
Volume 6, Issue 3 (May/June 2009)
2Carl G.H. Dahlöf, MD, PhD, 3Lars Søndergaard, MD, 1Peter H. Hannam

Abstract

During the last decade, patent foramen ovale (PFO) and intermittent or permanent right-to-left shunting of venous blood has been proposed to play a pathogenetic role in a number of disorders. This review covers the most common and sometimes controversial indications for closure of the PFO. It considers the safety of the procedure, current evidence that supports closure, and counter arguments. It then offers a considered position for each indication.

Introduction

In recent years, there has been a great deal of attention paid to the patent foramen ovale (PFO). In



Catheter-Directed and Pharmacomechanical Thrombolysis for the Treatment of Acute Iliofemoral Deep Venous Thrombosis




VOLUME: 6 PUBLICATION DATE: Jun 01 2009
Issue Number: 
Volume 6, Issue 3 (May/June 2009)
Anthony J. Comerota, MD, FACS, FACC, Nina Grewal, MD

Introduction

The majority of physicians treat patients with iliofemoral deep venous thrombosis (DVT) with anticoagulation alone, despite a growing body of evidence that these patients suffer more severe postthrombotic morbidity and higher recurrence rates than patients with infrainguinal DVT. Although there have been enormous advances in anticoagulation therapy (e.g., low-molecular-weight heparins, pentasaccharides, and direct thrombin inhibitors), these agents serve to limit the progression of thrombosis and, with proper duration of therapy, reduce recurrence. However, anticoagulant



Why Thrombosis Prophylaxis Fails




VOLUME: 6 PUBLICATION DATE: Mar 16 2009
Issue Number: 
Volume 6, Issue 2 (March/April 2009)
Joseph A. Caprini, MD, MS, FACS, RVT

author affiliations:

From the Division of Vascular Surgery, NorthShore University Health System, Evanston, Illinois, Northwestern University Feinberg School of Medicine, Chicago, Illinois, and the Robert R. McCormick School of Bioengineering Northwestern University, Evanston, Illinois.

The author discloses no conflicts of interest regarding the content herein.

Manuscript submitted November 11, 2008, provisional acceptance given January 12, 2009, final version accepted January 30, 2009.

Address for correspondence: Joseph A. Caprini, MD, MS, FACS, Louis Biegler Professor of



Laser Venous Interventions




VOLUME: 6 PUBLICATION DATE: Mar 16 2009
Issue Number: 
Volume 6, Issue 2 (March/April 2009)
Daniel Carradice, MD and Ian Chetter, MD

author affiliations:

From the Academic Vascular Surgical Unit, Hull Royal Infirmary, E. Yorks, United Kingdom.

Disclosure: Dr. Carradice and Dr. Chetter disclose that Diomed (Cambridge, U.K.) provided research grants (50% of a research nurse’s salary over a 12-month period) to facilitate trials at Hull Royal Infirmary, but had no involvement or influence in the drafting, or decision to publish this or any other paper.

Manuscript submitted September 12, 2008, provisional acceptance given December 2, 2008, accepted December 11, 2008.

Address for correspondence: Daniel Carr



Optimal Strategy in Lower Extremity Peripheral Percutaneous Interventions: An Interventionalist’s Perspective




VOLUME: 6 PUBLICATION DATE: Mar 16 2009
Issue Number: 
Volume 6, Issue 2 (March/April 2009)
Nicolas W. Shammas, MD

author affiliations:

From the Midwest Cardiovascular Research Foundation, Davenport, Iowa.

Disclosure: Supported by the Nicolas and Gail Shammas Research Fund at the Midwest Cardiovascular Research Foundation (MCRF). MCRF has received research grants from ev3 and Foxhollow.

Manuscript submitted December 4, 2008 and accepted January 9, 2009.

Address for correspondence: Nicolas W. Shammas, MS, MD, Cardiovascular Medicine PC, 1236 E. Rusholme, Davenport, IA 52803 E-mail: shammas@mchsi.com

__________________________________

Abstract

Peripheral artery disease



The Aortic Arch: Markers, Imaging, and Procedure Planning for Carotid Intervention




VOLUME: 6 PUBLICATION DATE: Jan 01 2009
Issue Number: 
Volume 6, Issue 1 (Jan/Feb 2009)

Author:

Christos D. Liapis, MD, Efthimios D. Avgerinos, MD, Achilles Chatziioannou, MD

Author Affiliations:

From the University Hospital Attikon, Department of Vascular Surgery, Athens, Greece.

Correspondence: Christos D. Liapis, MD, University Hospital Attikon, Department of Vascular Surgery, 1 Rimini Street, Chaidari, Athens 12462, Greece. E-mail: liapis@med.uoa.gr.

Manuscript submitted September 15, 2008, provisional acceptance given, November 5, 2008, accepted November 13, 2008.

Disclosure: The authors report no financial relationships or conflicts of inte



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CME Showcase

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Release Date: December 22, 2008

Expiration Date: December 22, 2009

This activity is supported by an educational grant from PamLabs.
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